Intellectual Property
Intellectual Property
At the heart of Ractigen Therapeutics lies a strong intellectual property (IP) foundation, notably in the fields of RNA activation (RNAa) and oligonucleotide delivery. Central to our innovation is a high-throughput discovery engine, expertly designed for the swift identification of small activating RNAs (saRNAs). Our IP portfolio is strategically constructed upon both the composition of matter and methods of use, encompassing an expanding library of therapeutic oligonucleotides. The development of proprietary medicinal chemistries and delivery platforms, all created in-house, further solidifies our IP estate, providing a robust platform for advanced drug development
High-Throughput
Process
Our Discovery Engine
It features a highly-refined bioinformatics algorithm integrating epigenetic datasets, design rules, and genome-wide on-target prediction tethered to in-house oligonucleotide manufacturing for saRNA synthesis followed by automated experimental validation of saRNA activity.
Target Gene Locus
Rapidly identify all saRNAs for any single target gene
Search Algorithm
Highly-refined
bioinformatics algorithm
In-House Synthesis
Oligonucleotide manufacturing for in-house saRNA synthesis
In vitro Screening & Gene Expression
Automated rounds of dose-dependent gene expression
3-4 Weeks Start to Finish (All In-House)
Screen Hundreds of saRNA Candidates
Automated rounds of dose-dependent gene expression analytics and integrated de-risking safety assays allow for the screening of hundreds of saRNA candidates within 30-45 days.
Honing the Process
We are continually honing the process in pursuit of full-automation and continue to add to our ever-growing list of therapeutic genes expanding our IP estate and feeding our drug development pipeline.
Want to Discover More?
Check out our News. Below are some highlights to get you started.
Ractigen Therapeutics Announces Completion of Enrollment and First Dosing in Phase II Clinical Trial of RAG-17 for SOD1-ALS
Nantong, China, August 6, 2026 – Ractigen Therapeutics, a clinical-stage biotechnology company pioneering next-generation RNA…
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Ractigen Therapeutics Announces U.S. FDA IND Clearance for First-in-Class saRNA Candidate RAG-1C to Treat Proliferative Vitreoretinopathy
RAG-1C achieves dual IND clearances from both U.S. FDA and China CDE, paving the way…
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Ractigen Therapeutics Closes Over $31 Million Financing to Advance Clinical-Stage saRNA Pipeline and Proprietary Extrahepatic Delivery Platforms
Funding led by Guozhong Capital will accelerate Phase 2 development for saRNA candidate RAG-01 and…
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Ractigen Therapeutics Announces Landmark Publication in Nature Medicine Highlighting Unprecedented Preclinical Efficacy and Positive First-in-Human Clinical Data for RAG-17 in SOD1-ALS
— Peer-reviewed publication details RAG-17’s robust translation from "bench to bedside," validating the proprietary SCAD™…
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