Join Us
To Help Build a New Class of Oligonucleotide Therapeutics

Location: Shanghai / Suzhou

Reports To: Chief Business Officer

 

Position Overview

We are seeking a highly driven Business Development professional with a strong background in biology and top-tier consulting experience to join our team. The primary objective of this role is to drive the out-licensing of our early-stage oligonucleotide pipeline and explore co-development partnerships. The ideal candidate will leverage their scientific expertise and commercial acumen to identify strategic partners, conduct rigorous asset evaluations, and translate complex scientific data into compelling commercial narratives for senior leadership.

Key Responsibilities

1. Out-licensing & Partnership Sourcing: Proactively identify and evaluate global licensing-out and co-development opportunities for our oligonucleotide assets. Build and maintain a robust pipeline of potential partners, including mid-to-large-cap pharma companies and specialized biotechs.
2. Scientific & Commercial Evaluation: Lead scientific and commercial due diligence processes. Conduct in-depth market assessments, competitive landscape analyses, and unmet medical needs evaluations to build comprehensive business cases for out-licensing strategies.
3. Deal Execution & Negotiation Support: Build and maintain robust financial models (e.g., rNPV). Assist in structuring term sheets and actively participate in commercial negotiations with external partners to close transactions.
4. Executive Communication: Create high-quality, visually compelling PowerPoint presentations to articulate project value propositions, strategic rationale, and deal terms to the C-suite, Board of Directors, and external stakeholders.
5. Cross-functional Collaboration: Work closely with R&D, Clinical, IR and IP teams to ensure holistic project evaluation and seamless integration of external assets.

Qualifications & Requirements

Education

• Master’s degree or above in Biology, Molecular Biology, Biochemistry, Pharmacy, or a related life science field.

Experience Requirements

• 3-5 years of experience in a reputable management consulting firm (e.g., MBB, Big 4, or specialized healthcare consulting). Prior experience in Biotech BD, corporate development, or strategic investments focusing on early-stage assets is highly preferred.

Professional Skills

• Exceptional PowerPoint and storytelling skills, with a proven ability to synthesize complex scientific data into clear, persuasive visual narratives.
• Strong financial acumen, including proficiency in financial modeling and rNPV valuation.
• Deep understanding of therapeutic landscape and out-licensing deal structures.
• Fluent in both English and Mandarin (written and spoken), with excellent interpersonal skills to navigate cross-functional teams and external partners.

Job Location: Suzhou, Hefei

 

Position Overview

Ractigen Therapeutics is a clinical-stage biotechnology company pioneering the development of Small Activating RNA (saRNA) therapeutics. We are seeking highly motivated and talented scientists at all levels—from Senior Scientist to Director—to join our growing R&D team.

Successful candidates will play a pivotal role in advancing our RNA therapeutic pipeline. Depending on experience, you will serve as a Project Lead or Therapeutic Area Lead, driving programs from target evaluation and proposal through preclinical proof-of-concept (POC) to IND-enabling studies and regulatory filing.

Key Responsibilities

1. Project & Strategic Leadership (Scope varies by level)

• Scientist / Senior Scientist: Act as a key technical lead for specific projects; design and execute in vitro and in vivo studies to validate targets and screen RNA candidates.
• Associate Director: Serve as Project Lead; independently propose new drug discovery projects, design the critical path for PCC (Preclinical Candidate) selection, and manage cross-functional resources to meet timelines.
• Director: Serve as Therapeutic Area Lead; define the strategic roadmap for a specific disease area (e.g., CNS, Metabolic, Oncology); oversee the entire portfolio from concept to IND filing; manage and mentor a team of scientists.

2. Scientific Execution: Biology & Pharmacology

• Target Discovery: Conduct comprehensive literature reviews and bioinformatics analysis to identify and propose novel targets suitable for RNA therapeutics including saRNA and siRNA.
• Validation & Screening: Develop robust cellular assays (qPCR, Western Blot, ELISA, functional assays) to validate target engagement and screen oligonucleotide sequences.
• In Vivo Pharmacology: Design and oversee animal efficacy studies (mouse/rat/NHP); analyze PK/PD relationships to guide dose selection and optimization.

3. Preclinical Development & IND-Enabling

• Lead the transition of programs from discovery to development.
• Design and manage IND-enabling studies (GLP toxicology, safety pharmacology, biodistribution) in collaboration with internal teams and external CROs.
• Author and review pharmacology/biology sections of regulatory submissions (IND/CTA) to the NMPA, FDA, and other health authorities.

Qualifications

1. Education & Training (Required for All Levels)

• Ph.D. in Pharmacology, Biology, Biomedical Sciences, or a related discipline.
• Postdoctoral training in a reputable academic or industrial lab is highly preferred.

2. Experience Requirements

• Scientist / Senior Scientist: 0–4 years of post-PhD experience. Strong hands-on skills in molecular biology and animal handling.
• Associate Director: 5–8 years of industrial experience with a track record of leading projects from discovery to lead optimization.
• Director: 8+ years of industrial experience with proven success in advancing programs to IND filing. Experience managing teams is required.

3. Technical & Professional Skills

• Oligonucleotide Expertise: Prior experience in the discovery and development of RNA therapeutics (ASO, siRNA, saRNA, mRNA) is a strong plus.
• Drug Discovery Knowledge: Deep understanding of the drug discovery process, including assay development, in vivo pharmacology, and DMPK/Tox principles.
• Language: Excellent English communication skills (both spoken and written) are a MUST. Ability to write high-quality scientific reports and present complex data clearly.
• Soft Skills: Strong problem-solving abilities, adaptability, and a collaborative spirit in a fast-paced biotech environment.

How to Apply

Please submit your CV (in both English) and a Cover Letter indicating the level (Scientist/AD/Director) you are applying for to: hr@ractigen.com

Job Location:Suzhou

Report to: Chief Executive Officer (CEO)

 

Position Overview:

As a clinical-stage RNA therapeutics platform company entering a critical phase of global expansion, clinical execution, and strategic partnerships, Ractigen Therapeutics is seeking a dynamic and experienced VP/Senior Director of HR and Administration.

Reporting directly to the CEO, this leader will be a key member of the executive team, responsible for designing and executing the human resources strategy, organizational development, and overarching administrative operations. This role requires a hands-on yet strategic leader capable of attracting top-tier global talent, implementing robust performance management systems (KPIs/OKRs), fostering an innovative corporate culture, and ensuring that our facilities, EHS, and daily operations run efficiently to support our rapidly growing R&D and clinical teams.

Key Responsibilities:

1. Talent Acquisition & Employer Branding

• Develop and execute a comprehensive talent acquisition strategy to recruit top-tier scientific, clinical, and executive talent locally and globally.
• Partner closely with department heads to anticipate hiring needs, define organizational structures, and reduce time-to-hire for critical roles.
• Enhance Ractigen’s employer brand to position the company as an employer of choice within the competitive biopharmaceutical industry.

2. Performance Management & Total Rewards

• Design, implement, and optimize the company’s performance management systems (including SMART KPIs and probation evaluations) to drive accountability and high performance.
• Develop competitive compensation and benefits frameworks, including equity/stock option plans, annual bonus structures, and salary benchmarking to retain top talent.

3. Organizational Development & Culture

• Act as a trusted advisor to the CEO and senior management on all human capital matters, organizational design, and change management.
• Drive employee engagement initiatives and foster a collaborative, inclusive, and science-driven corporate culture across all company locations.
• Develop training, mentorship, and career progression pathways for both scientific and non-scientific staff.

4. Administration, Facilities & Lab Operations Support

• Oversee general administration, facility management, and site operations to ensure a safe, efficient, and highly productive working environment.
• Manage EHS (Environment, Health, and Safety) compliance, ensuring all R&D laboratories and office spaces meet strict industry and regulatory standards.
• Optimize procurement strategies for general administration and IT services, managing external vendors and optimizing operational budgets.

5. Compliance & Policy Development

• Develop, implement, and maintain HR and administrative policies, employee handbooks, and standard operating procedures (SOPs).
• Ensure full compliance with local labor laws, employment regulations, and safety standards in all regions where the company operates.

Qualifications & Requirements:

• Education: Bachelor’s degree in Human Resources, Business Administration, or a related field; Master’s degree or MBA is highly preferred.
• Experience: 10+ years of progressive HR and administrative operations experience, with at least 5 years in a senior leadership role within the biotech, pharmaceutical, or life sciences industry.
• Industry Knowledge: Deep understanding of the biotech ecosystem, including R&D workflows, clinical trial phases, and the unique talent profiles required (e.g., CMC, Clinical Ops, Discovery Bio, BD).
• Operational Excellence: Proven track record of scaling operations from early-stage/pre-clinical to clinical-stage/commercial-ready phases. Experience managing lab facilities and EHS is a strong plus.
• Leadership & EQ: Exceptional interpersonal and conflict-resolution skills. Able to bridge the gap between scientific/technical teams and corporate functions.
• Language: Bilingual proficiency in English and Mandarin Chinese is required for effective internal and external communication.

Job Location: Suzhou

Report to: Chief Executive Officer (CEO)

 

Position Overview

This position serves as a core role within the company, responsible for executing the organization’s vision, plans, and strategies through driving drug development, management, and leadership. The primary core business functional areas covered include, but are not limited to: CMC (Chemistry, Manufacturing, and Controls), Quality Assurance (QA), Regulatory Affairs, and serving as the company’s Head of Manufacturing.

This position is also responsible for managing the company’s internal oligonucleotide manufacturing team, as well as external CDMOs and CROs associated with Active Pharmaceutical Ingredient (API) and drug product development, manufacturing, and analytical activities, in support of the company’s drug development programs, while engaging in cross-functional collaboration with teams across Research & Development, Preclinical, Technology, Legal, Finance, Quality, and Regulatory Affairs.

This position is additionally responsible for the development and implementation of regulatory strategies for early-stage and IND-stage oligonucleotide programs to support the achievement of overall program objectives, while facilitating the submission of high-quality regulatory filings, including the direct preparation of submission content and the management of submission deliverables and timelines.

 

Key Responsibilities

1. CMC

• Responsible for the development of comprehensive manufacturing strategies and quality control for company’s oligonucleotide drugs.
• Ensures adherence to timelines and project alignment to meet group and company goals.
• Interacts with key scientific, preclinical and clinical research personnel within and outside Company to ensure timely and accurate regulatory compliance on CMC and QA matters.
• Communicate status of projects and activities at CMOs/CROs to management and stakeholders.
• Manages manufacturing team to ensure timely production of research oligos for various preclinical programs.
• Manage timelines for deliverables and ensure product quality.
• Draft RFPs for new oligonucleotide manufacturing projects; track manage and negotiate new proposals.
• Manage supply chain to ensure adequate preclinical and clinical supplies for current and up-coming developmental programs.
• Manage internal and external inventory of product retains, product samples, clinical supplies and outsourced product samples.
• Manage CMC outsourcing budget.
• Works closely with the Quality Control team to identify and resolve any relevant CMC issues.
• Develop and maintain performance metrics for team members and external partners.

2. QA

• Oversee the implementation and management of quality assurance policies implemented throughout all Ractigen facilities.
• Represent CMC/QA in cross-functional initiatives.
• Establishes and maintains QA metrics and/or dashboards to support Quality oversight.
• Establishes and/or leads vendor QA-QA relationships with preferred/critical CROs and vendors, including implementation of quality agreements, as applicable.
• Coordinates preparation activities for global regulatory agency inspections and other audits.
• Leads and/or contributes to the development of continuous quality process improvements.

3. Regulatory Affairs

• Lead the development, implementation, and execution of regulatory strategy.
• Ensure all regulatory submissions and projects align with defined regulatory strategy and proactively identify gaps/work with teams to develop mitigation proposals.
• Lead and manage preparation of high-quality regulatory submission content of the different sections to support global clinical development, registration and product life cycle management.
• Manage regulatory compliance activities including periodic regulatory reporting, review of technical documents, and providing regulatory assessments on deviations, CAPAs, change controls, etc.
• Actively participate/lead regulatory CMC infrastructure and capability building, including developing best practices, training tools, and cross-program learning.
• Oversee cross-functional efforts and resources and identify, track and report on critical path activities.

 

4. Statutory Role & Responsibilities (Head of Manufacturing)

• Serve as the company’s Statutory Head of Manufacturing under applicable PRC MAH and GMP regulations, and be accountable for the GMP compliance and maintained state of control of manufacturing operations (including contract manufacturing activities).
• Establish, maintain and ensure effective implementation of manufacturing management systems, including manufacturing procedures, batch documentation governance, training/qualification, and shop-floor compliance.
• Ensure each batch is manufactured strictly in accordance with approved procedures and master batch records; ensure batch records are complete, accurate, contemporaneous and traceable; ensure deviations are timely reported and managed.
• Lead or ensure effective investigation and CAPA implementation for manufacturing-related deviations/events (including sterile assurance and contamination control related events), and ensure appropriate escalation and impact assessment.
• Ensure manufacturing-related changes are executed under an approved change control system; ensure execution of validation/qualification activities relevant to manufacturing operations (e.g., equipment qualification, process validation support, cleaning validation execution as applicable).
• Ensure sterile manufacturing operations for injectable oligonucleotide products are conducted in compliance with GMP requirements, including implementation of contamination control strategy (CCS), personnel qualification, aseptic practices and environmental monitoring program execution (manufacturing responsibilities).
• Oversee manufacturing-related aspects of contract manufacturing, including ensuring effective communication and escalation, timely review of manufacturing documentation, and implementation of agreed CAPA/changes by the CDMO (in coordination with QA and CMC).
• Note: Final batch release decision is made by Quality (QA) in accordance with the company Quality System. The Head of Manufacturing is accountable for compliant batch execution and completeness/accuracy of manufacturing documentation to support QA disposition and release.

 

Qualifications & Requirements

1. Statutory Eligibility (PRC)

In accordance with applicable PRC regulations for MAH and contract manufacturing, the Head of Manufacturing shall meet the following requirements:

•  Holds a bachelor’s degree or above in pharmacy or a related discipline, or possesses an intermediate or higher professional and technical title, or holds a licensed pharmacist qualification.
• Possesses a minimum of three years of practical experience in pharmaceutical manufacturing and quality management, of which at least one year shall be directly related to pharmaceutical production management.
• Demonstrates comprehensive familiarity with the laws, regulations, and regulatory requirements governing pharmaceutical manufacturing management.
• Possesses comprehensive product knowledge relevant to the contracted manufacturing products.
• For the contract manufacturing of sterile pharmaceutical products, the Head of Manufacturing of the Marketing Authorization Holder (MAH) shall have accumulated a minimum of five years of practical experience in pharmaceutical manufacturing and quality management, of which at least three years shall be directly related to the manufacturing and quality management of sterile pharmaceutical products.

2. Requires a Ph.D. in chemistry or related field and strong specialization in oligonucleotide-based space.
3. 8 or more years’ experience in industry relating to chemical synthesis, process development and CMC with successful IND/NDA submissions and commercialization of products; experience with siRNA/Oligonucleotide is required.
4. Strong understanding of CMC development for oligonucleotide therapeutics, including control strategy, specifications, comparability, and technology transfer.
5. Direct relevant experience in method development and validation and use of appropriate analytical methodologies for oligonucleotide-based therapeutics.
6. Experience with CMC regulatory aspects for oligonucleotide therapeutics.
7. Proven leadership experience in CMC/Technical Operations and Quality functions in a biopharmaceutical company.
8. Excellent analytical, presentation, and writing skills are required.
9. Senior managerial experience in a small company environment is desirable.
10. Excellent interpersonal skills and ability to work efficiently and productively in a highly dynamic environment.
11. Knowledge of cGMP, cGLP, ICH, USP and FDA guidelines and regulations.

Job Location: Shanghai / Suzhou

Report to: Chief Executive Officer (CEO)

Position Overview

Ractigen Therapeutics is a highly differentiated, clinical-stage RNA therapeutics platform company with a robust pipeline of innovative programs. As we enter a transformative phase of corporate growth, we are seeking a seasoned, strategic, and hands-on Chief Financial Officer (CFO) to lead the company into its next critical milestone: a successful Initial Public Offering (IPO) on the Hong Kong Stock Exchange (HKEX).

The CFO will act as a key strategic partner to the CEO and the Board of Directors. The primary mandate of this role is to architect and execute the company’s capital markets strategy, drive pre-IPO crossover financing, lead the HKEX listing process (under Chapter 18A), and upgrade the company’s financial operations, internal controls, and corporate governance to public-company standards.

Key Responsibilities

1. Capital Markets Strategy & HKEX IPO Execution

• Lead the HKEX IPO Process: Serve as the internal project lead for the upcoming HKEX listing. Manage the entire process from kick-off to A1 submission and final listing.
• Manage External Advisors: Select and closely coordinate with sponsors, investment banks, legal counsels, and independent auditors to ensure a smooth, compliant, and timely IPO timeline.
• Prospectus Preparation: Work closely with the scientific and clinical teams to translate Ractigen’s platform and clinical pipeline data into a compelling equity story and finalize the IPO prospectus.

2. Corporate Finance & Fundraising

• Pre-IPO / Crossover Financing: Formulate the financing strategy and successfully close the Pre-IPO/Crossover funding round to ensure sufficient cash runway prior to and through the IPO.
• Capital Structure Optimization: Continuously evaluate and optimize the company’s capital structure, exploring non-dilutive funding, debt financing, and strategic equity investments.

3. Investor Relations (IR) & Board Management

• Establish IR Function: Build a proactive Investor Relations strategy. Cultivate and maintain strong relationships with institutional investors, buy-side/sell-side analysts, and financial media.
• Roadshows & Pitching: Lead global deal roadshows and investor meetings, confidently articulating Ractigen’s clinical milestones, platform differentiation, and financial health.
• Board of Directors: Serve as the primary financial liaison to the Board. Prepare and present high-quality financial reporting, audit committee updates, and strategic capital allocation plans at Board meetings.

4. Strategic FP&A & Business Partnership

• Resource Allocation: Partner with R&D, Clinical, and CMC leadership to develop rigorous budgets for global multi-center clinical trials and manufacturing scale-up. Ensure disciplined ROI on R&D spend.
• BD Financial Modeling: Work closely with the Chief Business Officer (CBO) to provide financial modeling, valuation, and structuring support for out-licensing deals, platform partnerships, and strategic M&A.

5. Corporate Governance, Compliance & Internal Controls

• Public Readiness: Upgrade the internal financial infrastructure, ERP systems, and internal control frameworks to comply with HKEX listing rules and post-listing regulatory requirements (IFRS/HKFRS).
• Risk Management: Establish robust enterprise risk management (ERM) policies, overseeing financial risk, FX exposure, and global tax planning for multinational operations (e.g., US/China entities).

6. Financial Reporting & HKEX Disclosure Management (Compliance Core)

• Consolidated Financial Statements: Coordinate the preparation of monthly, quarterly, and annual consolidated financial statements, strictly complying with HKFRS/IFRS and HKEX disclosure requirements to ensure accuracy and timeliness.
• HKEX Disclosure & Filings: Lead the preparation, review, and publication of the financial sections of HKEX disclosure documents, including annual/interim reports, circulars, and announcements.
• External Audit Management: Act as the primary liaison with external auditors, lead annual/interim audits, and follow up on adjustments and responses to ensure an unqualified audit opinion.
• Board & Audit Committee Reporting: Report performance results, key metrics, significant accounting judgments, and financial risks to the Board of Directors and Audit Committee.
• Financial Compliance: Responsible for the financial compliance and disclosure of connected transactions, use of proceeds, share incentive schemes, and dividend payouts.

Near-Term Key Objectives (First 12-18 Months)

1. Fundraising: Successfully close a Pre-IPO / Crossover round to bridge the company to a public listing.
2. IPO Readiness: Complete internal financial audits, finalize the internal control system upgrade, and assemble the IPO syndicate (bankers, lawyers, auditors).
3. A1 Submission: Lead the preparation and successful submission of the A1 application to the HKEX.

Qualifications & Requirements

• Education: Bachelor’s degree in Finance, Accounting, or Economics; MBA or advanced degree preferred. Active CPA, ACCA, CFA, or equivalent professional qualification is highly desirable.
• Experience: 15+ years of progressive financial leadership experience, with at least 5 years serving as CFO, VP of Finance, or Head of Capital Markets in the biopharmaceutical or life sciences industry.
• IPO Track Record (Crucial): Must have hands-on experience leading or playing a pivotal role in a successful IPO process, preferably on the HKEX (Chapter 18A). Experience in post-IPO public company financial management is a strong plus.
• Industry Knowledge: Deep understanding of the biotech business model, including clinical trial financing, CMC capitalization, and biotech valuation methodologies.
• Capital Market Network: Established relationships with top-tier healthcare/biotech institutional investors, crossover funds, and major investment banks in Asia and globally.
• Language: Bilingual proficiency in English and Mandarin Chinese is mandatory, with the ability to draft sophisticated financial narratives in both languages.
• Personal Attributes: High ethical standards, resilience under pressure, extremely detail-oriented while maintaining a strategic mindset.